Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
pak2bNon-specific serine/threonine protein kinase. (537 aa)    
Predicted Functional Partners:
pak1
Non-specific serine/threonine protein kinase.
   
  0.979
cdc42
Cell division cycle 42.
   
 0.976
arhgef6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6.
   
 0.954
cdc42l
Cell division cycle 42,-like.
   
 0.944
nck2b
Cytoplasmic protein.
    
 0.940
arhgef7b
Rho guanine nucleotide exchange factor (GEF) 7b.
   
 0.939
cdc42l2
Cell division cycle 42-like 2.
   
 0.938
rac2
Rac family small GTPase 2.
    
 0.937
nck2a
Cytoplasmic protein.
    
 0.927
nck1a
NCK adaptor protein 1a.
    
 0.927
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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