Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
fkbp1abPeptidylprolyl isomerase. (108 aa)    
Predicted Functional Partners:
ryr1b
Ryanodine receptor 1b (skeletal).
    
 
 0.859
mtor
Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.
    
 
 0.833
ryr3
Ryanodine receptor 3.
    
 
 0.803
ryr1a
Ryanodine receptor 1a (skeletal).
    
 
 0.763
ryr2b
Ryanodine receptor 2b (cardiac).
   
 
 0.752
RYR2
Uncharacterized protein.
    
 
 0.749
tgfbr1b
Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    
 0.668
tgfb1a
Transforming growth factor beta; Belongs to the TGF-beta family.
    
 0.647
rptor
Regulatory-associated protein of MTOR, complex 1.
    
 
 0.641
rps15
Ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family.
   
   0.627
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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