Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sash1aSAM and SH3 domain-containing 1a. (1192 aa)    
Predicted Functional Partners:
trmt11
tRNA methyltransferase 11 homolog.
      
 0.924
ficd
Protein adenylyltransferase FICD; Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.
      
 0.883
btr30
Bloodthirsty-related gene family, member 30.
   
  
 0.719
SAMD5
Sterile alpha motif domain containing 5.
 
    
0.706
mmrn2a
Multimerin 2a.
      
 0.668
hcrt
Hypocretin (orexin) neuropeptide precursor.
     
 0.608
slc22a2
Solute carrier family 22 member 2.
      
 0.595
sart3
Squamous cell carcinoma antigen recognized by T-cells 3; U6 snRNP-binding protein that functions as a recycling factor of the splicing machinery. Promotes the initial reassembly of U4 and U6 snRNPs following their ejection from the spliceosome during its maturation. May also function as a substrate targeting factor for deubiquitinases and mediate the deubiquitination of components of the spliceosome and histones (By similarity).
      
 0.594
ikbkb
Inhibitor of nuclear factor kappa B kinase subunit beta.
   
 
 0.529
mtrf1l
Mitochondrial translational release factor 1-like.
      
 0.500
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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