Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pdlim1PDZ and LIM domain 1 (elfin). (322 aa)    
Predicted Functional Partners:
pdlim4
PDZ and LIM domain 4.
     
0.990
pdlim2
PDZ and LIM domain 2 (mystique).
     
0.988
pdlim7
PDZ and LIM domain protein 7; May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues (By similarity).
   
 
0.942
pdlim5b
PDZ and LIM domain 5b.
   
 
 
0.924
ENSDARP00000154609
Uncharacterized protein.
   
 
  0.924
pdlim3b
PDZ and LIM domain 3b.
     
  0.916
gas2l3
Growth arrest-specific 2-like 3.
    
  0.913
pdlim3a
PDZ and LIM domain 3a.
  
  
0.906
specc1la
Cytospin-A; Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration (By similarity).
   
  0.901
specc1
Sperm antigen with calponin homology and coiled-coil domains 1.
   
  0.901
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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