Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
txn2Thioredoxin 2. (166 aa)    
Predicted Functional Partners:
txnipa
Thioredoxin-interacting protein a.
    
 0.992
TXN
Thioredoxin; Belongs to the thioredoxin family.
  
0.975
txn
Thioredoxin; Belongs to the thioredoxin family.
  
0.973
prdx3
Peroxiredoxin 3.
  
 0.972
map3k5
Mitogen-activated protein kinase kinase kinase 5.
    
 0.950
txnrd2.2
Thioredoxin reductase 2, tandem duplicate 2.
  
 0.950
ENSDARP00000146561
Si:ch211-1i11.3.
    
 0.950
txnipb
Thioredoxin-interacting protein b.
    
 0.922
prdx5
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.920
daxx
Death-domain-associated protein.
    
 0.917
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.