node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ASS1 | aldh18a1 | ENSDARP00000140635 | ENSDARP00000137162 | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.798 |
ASS1 | gart | ENSDARP00000140635 | ENSDARP00000131447 | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | Phosphoribosylglycinamide formyltransferase. | 0.736 |
ASS1 | gpr143 | ENSDARP00000140635 | ENSDARP00000047079 | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | G protein-coupled receptor 143. | 0.923 |
ASS1 | otc | ENSDARP00000140635 | ENSDARP00000083959 | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.997 |
ASS1 | umps | ENSDARP00000140635 | ENSDARP00000035728 | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | Uridine monophosphate synthetase. | 0.640 |
FRMD7 | gpr143 | ENSDARP00000126774 | ENSDARP00000047079 | Si:ch211-243g6.3. | G protein-coupled receptor 143. | 0.833 |
aldh18a1 | ASS1 | ENSDARP00000137162 | ENSDARP00000140635 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | 0.798 |
aldh18a1 | gart | ENSDARP00000137162 | ENSDARP00000131447 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Phosphoribosylglycinamide formyltransferase. | 0.777 |
aldh18a1 | gpr143 | ENSDARP00000137162 | ENSDARP00000047079 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | G protein-coupled receptor 143. | 0.916 |
aldh18a1 | oca2 | ENSDARP00000137162 | ENSDARP00000123879 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Oculocutaneous albinism II. | 0.647 |
aldh18a1 | otc | ENSDARP00000137162 | ENSDARP00000083959 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.702 |
aldh18a1 | umps | ENSDARP00000137162 | ENSDARP00000035728 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Uridine monophosphate synthetase. | 0.722 |
dhodh | gart | ENSDARP00000068087 | ENSDARP00000131447 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Phosphoribosylglycinamide formyltransferase. | 0.833 |
dhodh | gpr143 | ENSDARP00000068087 | ENSDARP00000047079 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | G protein-coupled receptor 143. | 0.793 |
dhodh | umps | ENSDARP00000068087 | ENSDARP00000035728 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Uridine monophosphate synthetase. | 0.999 |
frmd7 | gpr143 | ENSDARP00000122496 | ENSDARP00000047079 | FERM domain-containing 7. | G protein-coupled receptor 143. | 0.876 |
gart | ASS1 | ENSDARP00000131447 | ENSDARP00000140635 | Phosphoribosylglycinamide formyltransferase. | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | 0.736 |
gart | aldh18a1 | ENSDARP00000131447 | ENSDARP00000137162 | Phosphoribosylglycinamide formyltransferase. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.777 |
gart | dhodh | ENSDARP00000131447 | ENSDARP00000068087 | Phosphoribosylglycinamide formyltransferase. | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.833 |
gart | gpr143 | ENSDARP00000131447 | ENSDARP00000047079 | Phosphoribosylglycinamide formyltransferase. | G protein-coupled receptor 143. | 0.909 |