Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
clcn6Chloride channel 6; Belongs to the chloride channel (TC 2.A.49) family. (863 aa)    
Predicted Functional Partners:
ostm1
Osteoclastogenesis-associated transmembrane protein 1.
    
 
 0.873
agtrap
Angiotensin II receptor-associated protein.
      
 0.737
shroom1
Shroom family member 1.
      
 0.683
prpf3
PRP3 pre-mRNA-processing factor 3 homolog (yeast).
      
 0.671
cln5
Uncharacterized protein.
      
 0.657
g6pd
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.
  
  
 0.637
man2b1
Alpha-mannosidase.
      
 0.598
sgsh
N-sulfoglucosamine sulfohydrolase (sulfamidase).
   
  
 0.596
grid2ipb
Delphilin; Postsynaptic scaffolding protein.
    
 
 0.596
chrnb3b
Cholinergic receptor, nicotinic, beta polypeptide 3b.
      
 0.592
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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