Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ssr4Signal sequence receptor, delta. (168 aa)    
Predicted Functional Partners:
ssr3
Signal sequence receptor, gamma.
   
 0.999
ssr2
Translocon-associated protein subunit beta; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
   
 0.999
ssr1
Signal sequence receptor, alpha.
   
 0.998
sec61b
Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
   
 
 0.996
rpl8
60S ribosomal protein L8; Component of the large ribosomal subunit.
   
 
 0.970
rpl10
60S ribosomal protein L10; Component of the large ribosomal subunit (Probable). Plays a role in the formation of actively translating ribosomes. Plays a role in the embryonic brain development.
   
   0.960
rpl32
Ribosomal protein L32.
   
 
 0.954
rpl11
60S ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family.
   
 
 0.954
rpl19
60S ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family.
   
   0.952
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
   
   0.951
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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