| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| TXN | msra | ENSDARP00000045696 | ENSDARP00000047361 | Thioredoxin; Belongs to the thioredoxin family. | Methionine sulfoxide reductase A. | 0.916 |
| TXN | msrb1a | ENSDARP00000045696 | ENSDARP00000122736 | Thioredoxin; Belongs to the thioredoxin family. | Methionine-R-sulfoxide reductase B1-A; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Acts as a regulator of actin assembly by reducing methionine (R)-sulfoxide mediated by MICALs (mical1, mical2 or mical3) on actin, thereby promoting filament repolymerization. Plays a role in innate immunity by reducing oxidized actin, leading to [...] | 0.773 |
| TXN | msrb2 | ENSDARP00000045696 | ENSDARP00000012146 | Thioredoxin; Belongs to the thioredoxin family. | Methionine-R-sulfoxide reductase B2, mitochondrial; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maint [...] | 0.696 |
| TXN | msrb3 | ENSDARP00000045696 | ENSDARP00000122154 | Thioredoxin; Belongs to the thioredoxin family. | Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues. | 0.635 |
| TXN | selenoo1 | ENSDARP00000045696 | ENSDARP00000090475 | Thioredoxin; Belongs to the thioredoxin family. | Protein adenylyltransferase SelO-1, mitochondrial; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr and Tyr residues of target proteins (AMPylation). May be a redox-active mitochondrial selenoprotein which interacts with a redox target protein; Belongs to the SELO family. | 0.478 |
| TXN | selenow1 | ENSDARP00000045696 | ENSDARP00000117583 | Thioredoxin; Belongs to the thioredoxin family. | Selenoprotein W; Plays a role as a glutathione (GSH)-dependent antioxidant. May be involved in a redox-related process. May play a role in the myopathies of selenium deficiency (By similarity); Belongs to the SelWTH family. Selenoprotein W subfamily. | 0.488 |
| msra | TXN | ENSDARP00000047361 | ENSDARP00000045696 | Methionine sulfoxide reductase A. | Thioredoxin; Belongs to the thioredoxin family. | 0.916 |
| msra | msrb1a | ENSDARP00000047361 | ENSDARP00000122736 | Methionine sulfoxide reductase A. | Methionine-R-sulfoxide reductase B1-A; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Acts as a regulator of actin assembly by reducing methionine (R)-sulfoxide mediated by MICALs (mical1, mical2 or mical3) on actin, thereby promoting filament repolymerization. Plays a role in innate immunity by reducing oxidized actin, leading to [...] | 0.889 |
| msra | msrb2 | ENSDARP00000047361 | ENSDARP00000012146 | Methionine sulfoxide reductase A. | Methionine-R-sulfoxide reductase B2, mitochondrial; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maint [...] | 0.659 |
| msra | msrb3 | ENSDARP00000047361 | ENSDARP00000122154 | Methionine sulfoxide reductase A. | Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues. | 0.668 |
| msra | oplah | ENSDARP00000047361 | ENSDARP00000126999 | Methionine sulfoxide reductase A. | 5-oxoprolinase, ATP-hydrolysing. | 0.679 |
| msra | selenoj | ENSDARP00000047361 | ENSDARP00000142458 | Methionine sulfoxide reductase A. | Selenoprotein J. | 0.662 |
| msra | selenoo1 | ENSDARP00000047361 | ENSDARP00000090475 | Methionine sulfoxide reductase A. | Protein adenylyltransferase SelO-1, mitochondrial; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr and Tyr residues of target proteins (AMPylation). May be a redox-active mitochondrial selenoprotein which interacts with a redox target protein; Belongs to the SELO family. | 0.721 |
| msra | selenow1 | ENSDARP00000047361 | ENSDARP00000117583 | Methionine sulfoxide reductase A. | Selenoprotein W; Plays a role as a glutathione (GSH)-dependent antioxidant. May be involved in a redox-related process. May play a role in the myopathies of selenium deficiency (By similarity); Belongs to the SelWTH family. Selenoprotein W subfamily. | 0.729 |
| msra | tprg1l | ENSDARP00000047361 | ENSDARP00000089134 | Methionine sulfoxide reductase A. | Tumor protein p63-regulated 1-like. | 0.667 |
| msra | txn | ENSDARP00000047361 | ENSDARP00000064788 | Methionine sulfoxide reductase A. | Thioredoxin; Belongs to the thioredoxin family. | 0.694 |
| msrb1a | TXN | ENSDARP00000122736 | ENSDARP00000045696 | Methionine-R-sulfoxide reductase B1-A; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Acts as a regulator of actin assembly by reducing methionine (R)-sulfoxide mediated by MICALs (mical1, mical2 or mical3) on actin, thereby promoting filament repolymerization. Plays a role in innate immunity by reducing oxidized actin, leading to [...] | Thioredoxin; Belongs to the thioredoxin family. | 0.773 |
| msrb1a | msra | ENSDARP00000122736 | ENSDARP00000047361 | Methionine-R-sulfoxide reductase B1-A; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Acts as a regulator of actin assembly by reducing methionine (R)-sulfoxide mediated by MICALs (mical1, mical2 or mical3) on actin, thereby promoting filament repolymerization. Plays a role in innate immunity by reducing oxidized actin, leading to [...] | Methionine sulfoxide reductase A. | 0.889 |
| msrb1a | msrb2 | ENSDARP00000122736 | ENSDARP00000012146 | Methionine-R-sulfoxide reductase B1-A; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Acts as a regulator of actin assembly by reducing methionine (R)-sulfoxide mediated by MICALs (mical1, mical2 or mical3) on actin, thereby promoting filament repolymerization. Plays a role in innate immunity by reducing oxidized actin, leading to [...] | Methionine-R-sulfoxide reductase B2, mitochondrial; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maint [...] | 0.410 |
| msrb1a | selenoj | ENSDARP00000122736 | ENSDARP00000142458 | Methionine-R-sulfoxide reductase B1-A; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Acts as a regulator of actin assembly by reducing methionine (R)-sulfoxide mediated by MICALs (mical1, mical2 or mical3) on actin, thereby promoting filament repolymerization. Plays a role in innate immunity by reducing oxidized actin, leading to [...] | Selenoprotein J. | 0.736 |
