Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
mmp24Matrix metallopeptidase 24. (606 aa)    
Predicted Functional Partners:
timp2a
Tissue inhibitor of metalloproteinase 2.
    
 0.808
timp4.3
TIMP metallopeptidase inhibitor 4, tandem duplicate 3.
   
 0.774
timp4.1
TIMP metallopeptidase inhibitor 4, tandem duplicate 1.
    
 0.766
furina
Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family.
    
 0.721
phykpl
5-phosphohydroxy-L-lysine phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
      
 0.682
ube2v1
Ubiquitin-conjugating enzyme E2 variant 1.
     
  0.628
ENSDARP00000156938
Si:ch211-212d10.1; Belongs to the peptidase S1 family.
      
 0.557
furinb
Furin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family.
    
 
 0.554
ADAM12
ADAM metallopeptidase domain 12.
      
 0.547
hpxb
Hemopexin b.
      
 0.514
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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