STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
abcb11aATP-binding cassette, sub-family B (MDR/TAP), member 11a. (1320 aa)    
Predicted Functional Partners:
abcb11b
ATP-binding cassette, sub-family B (MDR/TAP), member 11b.
  
  
0.902
nr1h4
Nuclear receptor subfamily 1, group H, member 4.
   
 
 0.840
cyp7a1
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
   
 
 0.765
slc10a2
Solute carrier family 10 (Sodium/bile acid cotransporter family), member 2.
   
  
 0.669
cyp8b1
Cytochrome P450, family 8, subfamily B, polypeptide 1.
   
 
 0.665
nxph2b
Neurexophilin; May be signaling molecules that resemble neuropeptides.
      
 0.628
vipas39
Spermatogenesis-defective protein 39 homolog; Proposed to be involved in endosomal maturation implicating in part vps33b. In epithelial cells, the vps33b:vipas39 complex may play a role in the apical rab11a-dependent recycling pathway and in the maintenance of the apical-basolateral polarity. May play a role in lysosomal trafficking, probably via association with the core HOPS complex in a discrete population of endosomes; the functions seems to be indepenedent of vps33b. May play a role in vesicular trafficking during spermatogenesis (By similarity). May be involved in direct or indir [...]
      
 0.617
nxph2a
Neurexophilin; May be signaling molecules that resemble neuropeptides.
      
 0.586
rab11a
Novel protein similar to vertebrate Ras family.
   
 
 0.575
vps33a
VPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family.
   
 
 0.568
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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