STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
igf2bInsulin-like growth factor 2b. (212 aa)    
Predicted Functional Partners:
igf2r
Cation-independent mannose 6-phosphate receptor.
    
 
 0.958
igfbp2a
Insulin-like growth factor-binding protein 2-A; IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
   
 0.943
igf1rb
Tyrosine-protein kinase receptor.
    
 0.934
igf1ra
Tyrosine-protein kinase receptor.
    
 0.933
igfbp3
Insulin-like growth factor-binding protein 3.
   
 0.929
igfbp6b
Insulin-like growth factor-binding protein 6b.
   
 0.927
igfbp1a
Insulin-like growth factor-binding protein 1a.
   
 0.892
igfbp6a
Insulin-like growth factor-binding protein 6a.
   
 0.887
igfbp1b
Insulin-like growth factor-binding protein 1b.
   
 
 0.881
ide
Novel protein similar to H.sapiens IDE, insulin-degrading enzyme (IDE, zgc:162603); Belongs to the peptidase M16 family.
    
 
 0.869
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.