Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tfpiaTissue factor pathway inhibitor. (279 aa)    
Predicted Functional Partners:
thbd
Thrombomodulin.
    
 
 0.924
serpinc1
Serine (Or cysteine) proteinase inhibitor, clade C (Antithrombin), member 1; Belongs to the serpin family.
    
 
 0.870
serpind1
Serpin peptidase inhibitor, clade D (heparin cofactor), member 1; Belongs to the serpin family.
    
 
 0.785
f3a
Coagulation factor IIIa.
      
 0.756
f2
Coagulation factor II (thrombin); Belongs to the peptidase S1 family.
    
 
 0.739
vwf
Von Willebrand factor.
      
 0.699
ccdc61
Coiled-coil domain-containing protein 61.
      
 0.682
f3b
Coagulation factor IIIb.
      
 0.672
serpine1
Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family.
   
 
 0.634
adamts13
ADAM metallopeptidase with thrombospondin type 1 motif, 13.
      
 0.630
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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