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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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co-expression
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[Homology]
Score
ugcgUDP-glucose ceramide glucosyltransferase. (438 aa)    
Predicted Functional Partners:
b4galt5
Beta-1,4-galactosyltransferase 5; Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer) (By similarity). Required for proper patterning of the dorsoventral axis during embryogenesis through the regulation of BMP signaling. Plays a role in proteoglycan glycosylation that is required for BMP-dependent specification of the dorsoventral axis ; Belongs to the glycosyltransferase 7 family.
     
 0.988
degs1
Delta(4)-desaturase, sphingolipid 1.
   
 
 0.985
sgms2a
Sphingomyelin synthase 2a.
     
 0.984
b4galt6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6.
     
 0.982
asah1b
N-acylsphingosine amidohydrolase (acid ceramidase) 1b; Belongs to the acid ceramidase family.
     
 0.982
gba2
Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.
     
 0.982
cerk
Ceramide kinase.
    
 0.982
ugt8
UDP glycosyltransferase 8; Belongs to the UDP-glycosyltransferase family.
     
 0.981
asah1a
N-acylsphingosine amidohydrolase (acid ceramidase) 1a; Belongs to the acid ceramidase family.
     
 0.979
asah2
Neutral ceramidase; Plasma membrane ceramidase that hydrolyzes sphingolipid ceramides into sphingosine and free fatty acids at neutral pH. Ceramides, sphingosine, and its phosphorylated form sphingosine-1-phosphate are bioactive lipids that mediate cellular signaling pathways regulating several biological processes including cell proliferation, apoptosis and differentiation. Also catalyzes the reverse reaction allowing the synthesis of ceramides from fatty acids and sphingosine. Together with sphingomyelinase, participates in the production of sphingosine and sphingosine-1-phosphate fr [...]
     
 0.979
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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