Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tmem263Transmembrane protein 263. (120 aa)    
Predicted Functional Partners:
tmem264
Transmembrane protein 264.
      
 0.893
tmem251
Transmembrane protein 251.
      
 0.842
mlh3
MutL homolog 3 (E. coli).
      
 0.739
st7l
Suppressor of tumorigenicity 7 protein-like.
      
 0.736
pgap6
Transmembrane protein 8A.
      
 0.713
supt3h
SPT3 homolog, SAGA and STAGA complex component.
      
 0.681
gpr19
G protein-coupled receptor 19.
      
 0.674
grpr
Gastrin-releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.627
igfals
Insulin-like growth factor-binding protein, acid labile subunit.
      
 0.620
ing3
Inhibitor of growth protein.
      
 0.594
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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