Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
si:dkey-34e4.1Si:dkey-34e4.1. (628 aa)    
Predicted Functional Partners:
rasd1
RAS, dexamethasone-induced 1.
    
 0.914
nkap
NFKB activating protein-like.
    
   0.869
ENSDARP00000138168
Uncharacterized protein.
    
   0.825
nos2b
Nitric oxide synthase; Produces nitric oxide (NO).
    
 0.823
nos2a
Nitric oxide synthase; Produces nitric oxide (NO).
    
 0.823
nos1
Nitric oxide synthase; Produces nitric oxide (NO).
    
 0.823
pora
NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
    
 0.818
porb
NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
    
 0.818
mtrr
5-methyltetrahydrofolate-homocysteine methyltransferase reductase.
    
 0.818
pnn
Pinin, desmosome-associated protein.
    
   0.768
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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