Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
creld2Cysteine-rich with EGF-like domain protein 2; Possible role in neuronal acetylcholine receptor transport. Belongs to the CRELD family. (341 aa)    
Predicted Functional Partners:
manf
Mesencephalic astrocyte-derived neurotrophic factor.
   
  
 0.957
dnajb11
DnaJ heat shock protein family (Hsp40) member B11.
   
 
 0.936
pdia6
Protein disulfide isomerase family A, member 6; Belongs to the protein disulfide isomerase family.
   
  
 0.893
hyou1
Hypoxia up-regulated protein 1; Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding; Belongs to the heat shock protein 70 family.
   
 
 0.865
gmppb
Mannose-1-phosphate guanyltransferase beta; Catalyzes the formation of GDP-mannose, an essential precursor of glycan moieties of glycoproteins and glycolipids.
   
  
 0.858
sdf2l1
Stromal cell-derived factor 2-like 1.
   
 
 0.818
hspa5
Immunoglobulin binding protein; Belongs to the heat shock protein 70 family.
   
 
 0.797
cdk5rap1
CDK5 regulatory subunit-associated protein 1.
      
 0.734
hsp90b1
Heat shock protein 90, beta (Grp94), member 1.
   
  
 0.712
txndc5
Thioredoxin domain-containing 5; Belongs to the protein disulfide isomerase family.
   
  
 0.661
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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