Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nalcnSodium leak channel, non-selective. (1742 aa)    
Predicted Functional Partners:
unc80
Unc-80 homolog (C. elegans).
   
 
 0.986
fam155a
Family with sequence similarity 155 member A.
   
 
 0.978
fam155b
Transmembrane protein FAM155B.
   
 
 0.822
zgc:66101
Serine/threonine-protein kinase SIK3 homolog.
     
 0.756
plekhg2
Pleckstrin homology domain-containing, family G (with RhoGef domain) member 2.
     
 0.731
kcng1
Potassium voltage-gated channel, subfamily G, member 1; Belongs to the potassium channel family.
   
 
 0.702
nts
Neurotensin.
   
  
 0.675
scn2b
Voltage-gated sodium channel beta 2 subunit splice variant D.
   
 0.670
LOC100332538
Endothelin-converting enzyme-like 1.
   
  
 0.662
zc4h2
Zinc finger C4H2 domain-containing protein; Plays a role in GABAergic and V2 interneurons differentiation. Involved in motoneuron development and in neuromuscular junction formation.
      
 0.661
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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