Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
prkar2aaProtein kinase, cAMP-dependent, regulatory, type II, alpha A. (397 aa)    
Predicted Functional Partners:
prkar2ab
Protein kinase, cAMP-dependent, regulatory, type II, alpha, B.
  
  
 
0.994
PRKAR2B
Si:ch211-272n13.7.
  
  
 
0.994
prkacab
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily.
   
 0.993
prkar1ab
Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue-specific extinguisher 1) b.
  
  
 
0.993
prkar1b
Protein kinase, cAMP-dependent, regulatory, type I, beta.
  
  
 
0.993
prkar1aa
Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue-specific extinguisher 1) a.
  
  
 
0.991
prkacba
Protein kinase, cAMP-dependent, catalytic, beta a; Belongs to the protein kinase superfamily.
   
 0.987
prkacbb
Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily.
   
 0.970
prkx
Protein kinase X-linked; Belongs to the protein kinase superfamily.
   
 0.965
ENSDARP00000142524
Si:dkeyp-81f3.4.
    
  0.956
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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