Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
c8gComplement component 8, gamma polypeptide; Belongs to the calycin superfamily. Lipocalin family. (209 aa)    
Predicted Functional Partners:
c8b
Complement component 8, beta polypeptide.
   
 0.999
c5
Complement component 5.
   
 0.999
c8a
Complement component 8, alpha polypeptide.
   
 0.999
c9
Complement component 9.
   
 0.996
c7b
Complement component 7b.
   
 0.994
c7a
Complement component 7a.
     
 0.978
LOC798694
Complement component 6.
     
  0.900
c6
Complement component 6.
     
  0.900
c1qc
Complement component 1, q subcomponent, C chain.
   
  
 0.762
masp2
Mannan-binding lectin serine peptidase 2; Belongs to the peptidase S1 family.
   
 
 0.743
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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