Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rgp1RGP1 retrograde golgi transport homolog (S. cerevisiae). (386 aa)    
Predicted Functional Partners:
RIC1
RIC1 homolog, RAB6A GEF complex partner 1.
    
 0.996
rab6a
RAB6A, member RAS oncogene family.
    
 
 0.920
rab6bb
RAB6B, member RAS oncogene family b.
    
 
 0.619
rab41
RAB41, member RAS oncogene family.
    
 
 0.619
rab6ba
RAB6B, member RAS oncogene family a.
    
 
 0.619
ENSDARP00000153555
Uncharacterized protein.
    
 
 0.619
tmem38a
Trimeric intracellular cation channel type A; Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.
      
 0.596
cog6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
    
 
 0.595
cog8
Conserved oligomeric Golgi complex subunit 8; Belongs to the COG8 family.
    
 
 0.594
lamtor3
Ragulator complex protein LAMTOR3; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity).
   
 
  0.552
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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