STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
runx2bRUNX family transcription factor 2b. (478 aa)    
Predicted Functional Partners:
sp7
Sp7 transcription factor.
   
 
 0.954
col10a1a
Collagen, type X, alpha 1a.
   
  
 0.838
cbfb
Core-binding factor subunit beta.
   
 
 0.833
sox9a
HMG box transcription factor Sox9a.
   
 
 0.795
ctsk
Cathepsin K; Belongs to the peptidase C1 family.
   
  
 0.764
col2a1a
Collagen, type II, alpha 1a.
      
 0.746
bmp2b
Bone morphogenetic protein 2b.
   
  
 0.706
sparc
Secreted protein, acidic, cysteine-rich (osteonectin).
      
 0.703
bmp2a
Bone morphogenetic protein 2a.
   
  
 0.688
tnfsf11
TNF superfamily member 11; Belongs to the tumor necrosis factor family.
      
 0.680
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.