Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tekt4Tektin 4. (451 aa)    
Predicted Functional Partners:
tekt2
Tektin 2 (testicular).
  
 
0.943
cfap52
Cilia and flagella-associated protein 52.
   
 
 0.923
efhc1
EF-hand domain (C-terminal)-containing 1.
   
 
 0.922
cfap126
Protein Flattop; Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. Belongs to the Flattop family.
   
 
 0.896
efhc2
EF-hand domain-containing family member C2.
   
 
 0.877
cfap20
Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation (By similarity). Plays a role in cilia stability.
    
 
 0.875
ccdc113
Coiled-coil domain-containing protein 113; May be involved in primary cilium formation.
   
 
 0.870
cyb5d1
Cytochrome b5 domain-containing protein 1; Belongs to the cytochrome b5 family.
   
 
 0.867
ttc25
Tetratricopeptide repeat protein 25; Required for the docking of the outer dynein arm to cilia, hence plays an essential role in cilia motility.
   
 
 0.865
efhb
EF-hand domain family, member B.
   
   0.863
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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