Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
net1Neuroepithelial cell-transforming 1. (551 aa)    
Predicted Functional Partners:
scamp2
Secretory carrier-associated membrane protein.
    
 
 0.755
mybpc2a
Myosin-binding protein Ca.
   
  
 0.720
magi1a
Membrane-associated guanylate kinase, WW and PDZ domain-containing 1a.
    
   0.697
magi1b
Membrane-associated guanylate kinase, WW and PDZ domain-containing 1b.
    
   0.697
scn4aa
Sodium channel protein type 4 subunit alpha A; Pore-forming subunit of a voltage-gated sodium channel complex through which Na(+) ions pass in accordance with their electrochemical gradient. Alternates between resting, activated and inactivated states. Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles. Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.4/SCN4A subfamily.
      
 0.606
rhoab
Rho-related GTP-binding protein RhoA-B; Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers.
   
 0.603
mylk5
Myosin, light chain kinase 5.
   
  
 0.596
parp1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
      
 0.582
rhocb
Rho-related GTP-binding protein RhoA-D; Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers.
    
 0.526
rnd3b
Ras-like protein Rnd3b.
    
 0.526
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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