Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cmtr1Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1; S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG- capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway. (829 aa)    
Predicted Functional Partners:
dhx15
DEAH (Asp-Glu-Ala-His) box helicase 15.
   
 
 0.951
rngtt
Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus (By similarity).
    
 
 0.863
usta
Uronyl 2-sulfotransferase a.
      
 0.759
LOC110440168
EWS RNA-binding protein 1b.
    
 
 0.737
trmt44
tRNA methyltransferase 44 homolog.
      
 0.728
ewsr1b
Ewing sarcoma breakpoint region 1b.
    
 
 0.676
ccdc92
Coiled-coil domain-containing 92.
      
 0.641
pnrc1
Proline-rich nuclear receptor coactivator 1.
      
 0.630
TOM1L2
Target of myb1 like 2 membrane trafficking protein; Belongs to the TOM1 family.
   
  
 0.624
tom1l2
Target of myb1-like 2 membrane-trafficking protein; Belongs to the TOM1 family.
   
  
 0.624
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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