STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cmtr1Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1; S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG- capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway. (829 aa)    
Predicted Functional Partners:
usta
Uronyl 2-sulfotransferase a.
      
 0.834
LOC110440168
EWS RNA-binding protein 1b.
    
 
 0.755
trmt44
tRNA methyltransferase 44 homolog.
   
  
 0.748
mark3a
Non-specific serine/threonine protein kinase.
   
  
 0.731
TOM1L2
Target of myb1 like 2 membrane trafficking protein; Belongs to the TOM1 family.
   
  
 0.697
tom1l2
Target of myb1-like 2 membrane-trafficking protein; Belongs to the TOM1 family.
   
  
 0.697
ewsr1b
Ewing sarcoma breakpoint region 1b.
   
 
 0.684
bud23
BUD23 rRNA methyltransferase and ribosome maturation factor.
      
 0.663
fubp1
Far upstream element (FUSE)-binding protein 1.
   
  
 0.646
trmt2b
tRNA (uracil(54)-C(5))-methyltransferase homolog-B; Probable S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNA. May also have a role in tRNA stabilization or maturation (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
   
  
 0.626
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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