Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ankrd9Ankyrin repeat domain 9. (287 aa)    
Predicted Functional Partners:
kctd9b
Potassium channel tetramerization domain-containing 9b.
      
 0.766
npy8br
Neuropeptide Y /peptide YY receptor Yb; Belongs to the G-protein coupled receptor 1 family.
      
 0.734
commd5
COMM domain-containing 5.
    
 0.709
dnajc17
DnaJ (Hsp40) homolog, subfamily C, member 17.
   
  
 0.700
ibtk
Inhibitor of Bruton agammaglobulinemia tyrosine kinase.
    
 
 0.697
impdh2
Inosine-5'-monophosphate dehydrogenase 2; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
    
 
 0.695
tnfaip8l3
Tumor necrosis factor alpha-induced protein 8-like protein 3; May act as a lipid transfer protein. Belongs to the TNFAIP8 family.
      
 0.662
kctd9a
Potassium channel tetramerization domain-containing 9a.
      
 0.646
kcmf1
E3 ubiquitin-protein ligase KCMF1; Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination; Belongs to the KCMF1 family.
    
 
 0.643
impdh1a
Inosine-5'-monophosphate dehydrogenase 1a; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
    
 
 0.635
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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