STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
crybgxCrystallin beta gamma X; Belongs to the beta/gamma-crystallin family. (207 aa)    
Predicted Functional Partners:
opn1lw2
Red-sensitive opsin-2; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
   
  
 0.762
icn2
Protein S100; Belongs to the S-100 family.
      
 0.719
BFSP1
Beaded filament structural protein 1.
   
  
 0.674
kcna6a
Potassium voltage-gated channel, shaker-related, subfamily, member 6 a; Belongs to the potassium channel family.
   
  
 0.671
tgm1l3
Transglutaminase 1-like 3.
   
  
 0.645
gna14
Guanine nucleotide-binding protein (G protein), alpha 14.
      
 0.630
cryaa
Crystallin, alpha A; Belongs to the small heat shock protein (HSP20) family.
   
  
 0.623
impg2b-2
Interphotoreceptor matrix proteoglycan 2b.
      
 0.567
cox20
Cytochrome c oxidase assembly protein COX20, mitochondrial; Essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Acts as a chaperone in the early steps of cytochrome c oxidase subunit II (MT- CO2/COX2) maturation, stabilizing the newly synthesized protein and presenting it to metallochaperones SCO1/2 which in turn facilitates the incorporation of the mature MT-CO2/COX2 into the assembling CIV holoenzyme; Belongs to the COX20 family.
      
 0.542
fabp11b
Adipocyte fatty acid-binding protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
      
 0.480
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.