Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ctnnb1 | fzd2 | ENSDARP00000139205 | ENSDARP00000071107 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.940 |
| ctnnb1 | fzd3a | ENSDARP00000139205 | ENSDARP00000084982 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Transmembrane receptor frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.686 |
| ctnnb1 | fzd4 | ENSDARP00000139205 | ENSDARP00000139144 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.830 |
| ctnnb1 | fzd5 | ENSDARP00000139205 | ENSDARP00000036600 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.769 |
| ctnnb1 | fzd8a | ENSDARP00000139205 | ENSDARP00000066834 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.603 |
| ctnnb1 | lrp5 | ENSDARP00000139205 | ENSDARP00000108864 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Low density lipoprotein receptor-related protein 5. | 0.992 |
| ctnnb1 | sfrp1a | ENSDARP00000139205 | ENSDARP00000051490 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Secreted frizzled-related protein 1a. | 0.775 |
| ctnnb1 | sfrp2 | ENSDARP00000139205 | ENSDARP00000093275 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Secreted frizzled-related protein 2. | 0.767 |
| ctnnb1 | sfrp5 | ENSDARP00000139205 | ENSDARP00000056995 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Secreted frizzled-related protein 5. | 0.823 |
| ctnnb1 | wnt8b | ENSDARP00000139205 | ENSDARP00000049623 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Protein Wnt-8b; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. May play a role in the establishment of polarity in the nervous system. | 0.850 |
| fzd2 | ctnnb1 | ENSDARP00000071107 | ENSDARP00000139205 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | 0.940 |
| fzd2 | fzd5 | ENSDARP00000071107 | ENSDARP00000036600 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.627 |
| fzd2 | fzd8a | ENSDARP00000071107 | ENSDARP00000066834 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. | Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.454 |
| fzd2 | lrp5 | ENSDARP00000071107 | ENSDARP00000108864 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. | Low density lipoprotein receptor-related protein 5. | 0.964 |
| fzd2 | sfrp1a | ENSDARP00000071107 | ENSDARP00000051490 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. | Secreted frizzled-related protein 1a. | 0.816 |
| fzd2 | sfrp2 | ENSDARP00000071107 | ENSDARP00000093275 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. | Secreted frizzled-related protein 2. | 0.724 |
| fzd2 | sfrp5 | ENSDARP00000071107 | ENSDARP00000056995 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. | Secreted frizzled-related protein 5. | 0.824 |
| fzd2 | wnt8b | ENSDARP00000071107 | ENSDARP00000049623 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt-8b; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. May play a role in the establishment of polarity in the nervous system. | 0.916 |
| fzd3a | ctnnb1 | ENSDARP00000084982 | ENSDARP00000139205 | Transmembrane receptor frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | 0.686 |
| fzd3a | lrp5 | ENSDARP00000084982 | ENSDARP00000108864 | Transmembrane receptor frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. | Low density lipoprotein receptor-related protein 5. | 0.919 |
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