Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sdcbpSyndecan-binding protein (syntenin). (307 aa)    
Predicted Functional Partners:
cd63
Tetraspanin.
   
 
 0.899
suox
Sulfite oxidase.
     
  0.872
cd81a
Tetraspanin.
    
 
 0.855
cyp7a1
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
     
 0.851
ch25hl1.2
Cholesterol 25-hydroxylase-like protein 1, member 2; May catalyze the formation of 25-hydroxycholesterol from cholesterol.
    
  0.835
cyp17a1
Cytochrome P450, family 17, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family.
     
  0.830
cyp27a7
Cytochrome P450, family 27, subfamily A, polypeptide 7; Belongs to the cytochrome P450 family.
     
  0.830
hsd3b7
Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase; Belongs to the 3-beta-HSD family.
     
  0.830
cyp17a2
Cytochrome P450, family 17, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family.
     
  0.830
sult2st2
Sulfotransferase; Belongs to the sulfotransferase 1 family.
     
  0.830
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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