| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aaas | ndc1 | ENSDARP00000130151 | ENSDARP00000016349 | Achalasia, adrenocortical insufficiency, alacrimia. | Nucleoporin NDC1; Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane (By similarity); Belongs to the NDC1 family. | 0.993 |
| aaas | nup133 | ENSDARP00000130151 | ENSDARP00000023984 | Achalasia, adrenocortical insufficiency, alacrimia. | Nuclear pore complex protein Nup133; Involved in poly(A)+ RNA transport (By similarity). Involved in nephrogenesis. | 0.942 |
| aaas | nup210 | ENSDARP00000130151 | ENSDARP00000086821 | Achalasia, adrenocortical insufficiency, alacrimia. | Nucleoporin 210. | 0.976 |
| aaas | nup214 | ENSDARP00000130151 | ENSDARP00000102382 | Achalasia, adrenocortical insufficiency, alacrimia. | Nucleoporin 214. | 0.855 |
| aaas | nup42 | ENSDARP00000130151 | ENSDARP00000050124 | Achalasia, adrenocortical insufficiency, alacrimia. | Nucleoporin NUP42; Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. | 0.981 |
| aaas | nup43 | ENSDARP00000130151 | ENSDARP00000064438 | Achalasia, adrenocortical insufficiency, alacrimia. | Nucleoporin 43. | 0.950 |
| aaas | nup88 | ENSDARP00000130151 | ENSDARP00000025718 | Achalasia, adrenocortical insufficiency, alacrimia. | Nucleoporin 88; Component of the nuclear pore complex. | 0.988 |
| aaas | nup93 | ENSDARP00000130151 | ENSDARP00000013627 | Achalasia, adrenocortical insufficiency, alacrimia. | Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. | 0.964 |
| aaas | nup98 | ENSDARP00000130151 | ENSDARP00000110413 | Achalasia, adrenocortical insufficiency, alacrimia. | Nucleoporin 98. | 0.941 |
| aaas | rae1 | ENSDARP00000130151 | ENSDARP00000015105 | Achalasia, adrenocortical insufficiency, alacrimia. | mRNA export factor; Plays a role in mitotic bipolar spindle formation. Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Belongs to the WD repeat rae1 family. | 0.906 |
| ndc1 | aaas | ENSDARP00000016349 | ENSDARP00000130151 | Nucleoporin NDC1; Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane (By similarity); Belongs to the NDC1 family. | Achalasia, adrenocortical insufficiency, alacrimia. | 0.993 |
| ndc1 | nup133 | ENSDARP00000016349 | ENSDARP00000023984 | Nucleoporin NDC1; Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane (By similarity); Belongs to the NDC1 family. | Nuclear pore complex protein Nup133; Involved in poly(A)+ RNA transport (By similarity). Involved in nephrogenesis. | 0.978 |
| ndc1 | nup210 | ENSDARP00000016349 | ENSDARP00000086821 | Nucleoporin NDC1; Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane (By similarity); Belongs to the NDC1 family. | Nucleoporin 210. | 0.990 |
| ndc1 | nup214 | ENSDARP00000016349 | ENSDARP00000102382 | Nucleoporin NDC1; Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane (By similarity); Belongs to the NDC1 family. | Nucleoporin 214. | 0.914 |
| ndc1 | nup42 | ENSDARP00000016349 | ENSDARP00000050124 | Nucleoporin NDC1; Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane (By similarity); Belongs to the NDC1 family. | Nucleoporin NUP42; Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. | 0.915 |
| ndc1 | nup43 | ENSDARP00000016349 | ENSDARP00000064438 | Nucleoporin NDC1; Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane (By similarity); Belongs to the NDC1 family. | Nucleoporin 43. | 0.954 |
| ndc1 | nup88 | ENSDARP00000016349 | ENSDARP00000025718 | Nucleoporin NDC1; Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane (By similarity); Belongs to the NDC1 family. | Nucleoporin 88; Component of the nuclear pore complex. | 0.981 |
| ndc1 | nup93 | ENSDARP00000016349 | ENSDARP00000013627 | Nucleoporin NDC1; Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane (By similarity); Belongs to the NDC1 family. | Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. | 0.997 |
| ndc1 | nup98 | ENSDARP00000016349 | ENSDARP00000110413 | Nucleoporin NDC1; Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane (By similarity); Belongs to the NDC1 family. | Nucleoporin 98. | 0.984 |
| ndc1 | rae1 | ENSDARP00000016349 | ENSDARP00000015105 | Nucleoporin NDC1; Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane (By similarity); Belongs to the NDC1 family. | mRNA export factor; Plays a role in mitotic bipolar spindle formation. Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Belongs to the WD repeat rae1 family. | 0.850 |
