Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
calm1bCalmodulin 1b. (149 aa)    
Predicted Functional Partners:
stra6
Receptor for retinol uptake stra6; Retinol transporter. Accepts retinol from the extracellular retinol-binding protein rbp4, mediates retinol transport across the cell membrane, and then transmits retinol to the cytoplasmic retinol- binding protein rbp1. Required for normal vitamin A homeostasis.
   
  0.907
phkb
Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.
    
 0.907
trpc4b
Transient receptor potential cation channel, subfamily C, member 4b; Belongs to the transient receptor (TC 1.A.4) family.
    
   0.900
calm1a
Calmodulin 1a.
  
  
0.812
calm3a
Calmodulin 3a (phosphorylase kinase, delta).
  
  
0.812
calm3b
Calmodulin 3b (phosphorylase kinase, delta).
  
  
0.811
calm2a
Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
  
  
0.810
mylkb
Myosin light chain kinase b.
    
 0.801
kcnn1a
Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1a.
    
 
 0.749
ppp3r1b
Protein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, b.
    
 0.737
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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