STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gna12aGuanine nucleotide-binding protein (G protein) alpha 12a. (385 aa)    
Predicted Functional Partners:
lpar1
Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.980
arhgef11
Rho guanine nucleotide exchange factor (GEF) 11.
    
 0.962
lpar4
Lysophosphatidic acid receptor 4; Belongs to the G-protein coupled receptor 1 family.
    
 0.961
arhgef12a
Rho guanine nucleotide exchange factor (GEF) 12a.
    
 0.944
arhgef1b
Rho guanine nucleotide exchange factor (GEF) 1b.
    
 0.944
arhgef12b
Rho guanine nucleotide exchange factor (GEF) 12b.
    
 0.944
cxcr4b
Chemokine (C-X-C motif), receptor 4b; Belongs to the G-protein coupled receptor 1 family.
    
 0.934
gng12a
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
 0.930
ENSDARP00000133096
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
 0.928
lpar2b
Lysophosphatidic acid receptor 2b; Belongs to the G-protein coupled receptor 1 family.
    
 0.925
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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