Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
btr12Bloodthirsty-related gene family, member 12. (562 aa)    
Predicted Functional Partners:
arhgef40
Rho guanine nucleotide exchange factor (GEF) 40.
      
 0.799
znf219
Zinc finger protein 219; Transcriptional regulator. Recognizes and binds to the core DNA sequence motif 5'-GGGGG-3'. Binds to the col2a1a promoter and activates col2a1a expression. Binds to the sncgb promoter and activates sncgb expression, as part of a complex with sox9a.
    
 
 0.782
igsf9ba
Immunoglobulin superfamily, member 9Ba.
    
 
 0.779
igsf9bb
Immunoglobulin superfamily, member 9Bb.
    
 
 0.779
b2ml
Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
      
 0.772
lygl1
Lysozyme g.
      
 0.685
ikbke
Inhibitor of nuclear factor kappa B kinase subunit epsilon.
    
 0.638
irak3
Interleukin-1 receptor-associated kinase 3.
    
 0.620
tap1
Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP).
      
 0.575
irf5
Interferon regulatory factor 5.
    
 
 0.550
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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