Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NPC1L1 | apoba | ENSDARP00000133903 | ENSDARP00000062792 | NPC1 like intracellular cholesterol transporter 1. | Apolipoprotein Ba. | 0.630 |
| NPC1L1 | npc2 | ENSDARP00000133903 | ENSDARP00000050398 | NPC1 like intracellular cholesterol transporter 1. | NPC intracellular cholesterol transporter 2; Intracellular cholesterol transporter which acts in concert with NPC1 and plays an important role in the egress of cholesterol from the lysosomal compartment. Unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes is transferred by NPC2 to the cholesterol-binding pocket in the N-terminal domain of NPC1. May bind and mobilize cholesterol that is associated with membranes. NPC2 binds cholesterol with a 1:1 stoichiometry. Can bind a variety of sterols, including lathosterol, desmosterol and the pl [...] | 0.843 |
| NPC1L1 | zgc:193725 | ENSDARP00000133903 | ENSDARP00000014574 | NPC1 like intracellular cholesterol transporter 1. | Zgc:193725. | 0.766 |
| adgre5b.3 | npc1 | ENSDARP00000137759 | ENSDARP00000144951 | Adhesion G protein-coupled receptor E5b, duplicate 3; Belongs to the G-protein coupled receptor 2 family. | Niemann-Pick disease, type C1. | 0.553 |
| adgre5b.3 | npc2 | ENSDARP00000137759 | ENSDARP00000050398 | Adhesion G protein-coupled receptor E5b, duplicate 3; Belongs to the G-protein coupled receptor 2 family. | NPC intracellular cholesterol transporter 2; Intracellular cholesterol transporter which acts in concert with NPC1 and plays an important role in the egress of cholesterol from the lysosomal compartment. Unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes is transferred by NPC2 to the cholesterol-binding pocket in the N-terminal domain of NPC1. May bind and mobilize cholesterol that is associated with membranes. NPC2 binds cholesterol with a 1:1 stoichiometry. Can bind a variety of sterols, including lathosterol, desmosterol and the pl [...] | 0.645 |
| apoba | NPC1L1 | ENSDARP00000062792 | ENSDARP00000133903 | Apolipoprotein Ba. | NPC1 like intracellular cholesterol transporter 1. | 0.630 |
| apoba | npc1 | ENSDARP00000062792 | ENSDARP00000144951 | Apolipoprotein Ba. | Niemann-Pick disease, type C1. | 0.413 |
| apoba | npc2 | ENSDARP00000062792 | ENSDARP00000050398 | Apolipoprotein Ba. | NPC intracellular cholesterol transporter 2; Intracellular cholesterol transporter which acts in concert with NPC1 and plays an important role in the egress of cholesterol from the lysosomal compartment. Unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes is transferred by NPC2 to the cholesterol-binding pocket in the N-terminal domain of NPC1. May bind and mobilize cholesterol that is associated with membranes. NPC2 binds cholesterol with a 1:1 stoichiometry. Can bind a variety of sterols, including lathosterol, desmosterol and the pl [...] | 0.654 |
| apoba | zgc:193725 | ENSDARP00000062792 | ENSDARP00000014574 | Apolipoprotein Ba. | Zgc:193725. | 0.565 |
| npc1 | adgre5b.3 | ENSDARP00000144951 | ENSDARP00000137759 | Niemann-Pick disease, type C1. | Adhesion G protein-coupled receptor E5b, duplicate 3; Belongs to the G-protein coupled receptor 2 family. | 0.553 |
| npc1 | apoba | ENSDARP00000144951 | ENSDARP00000062792 | Niemann-Pick disease, type C1. | Apolipoprotein Ba. | 0.413 |
| npc1 | npc2 | ENSDARP00000144951 | ENSDARP00000050398 | Niemann-Pick disease, type C1. | NPC intracellular cholesterol transporter 2; Intracellular cholesterol transporter which acts in concert with NPC1 and plays an important role in the egress of cholesterol from the lysosomal compartment. Unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes is transferred by NPC2 to the cholesterol-binding pocket in the N-terminal domain of NPC1. May bind and mobilize cholesterol that is associated with membranes. NPC2 binds cholesterol with a 1:1 stoichiometry. Can bind a variety of sterols, including lathosterol, desmosterol and the pl [...] | 0.999 |
| npc1 | smpd1 | ENSDARP00000144951 | ENSDARP00000124101 | Niemann-Pick disease, type C1. | Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. | 0.412 |
| npc1 | zgc:193725 | ENSDARP00000144951 | ENSDARP00000014574 | Niemann-Pick disease, type C1. | Zgc:193725. | 0.975 |
| npc1 | zgc:55413 | ENSDARP00000144951 | ENSDARP00000129266 | Niemann-Pick disease, type C1. | Zgc:55413. | 0.452 |
| npc1 | zgc:66024 | ENSDARP00000144951 | ENSDARP00000112506 | Niemann-Pick disease, type C1. | Zgc:66024. | 0.452 |
| npc2 | NPC1L1 | ENSDARP00000050398 | ENSDARP00000133903 | NPC intracellular cholesterol transporter 2; Intracellular cholesterol transporter which acts in concert with NPC1 and plays an important role in the egress of cholesterol from the lysosomal compartment. Unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes is transferred by NPC2 to the cholesterol-binding pocket in the N-terminal domain of NPC1. May bind and mobilize cholesterol that is associated with membranes. NPC2 binds cholesterol with a 1:1 stoichiometry. Can bind a variety of sterols, including lathosterol, desmosterol and the pl [...] | NPC1 like intracellular cholesterol transporter 1. | 0.843 |
| npc2 | adgre5b.3 | ENSDARP00000050398 | ENSDARP00000137759 | NPC intracellular cholesterol transporter 2; Intracellular cholesterol transporter which acts in concert with NPC1 and plays an important role in the egress of cholesterol from the lysosomal compartment. Unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes is transferred by NPC2 to the cholesterol-binding pocket in the N-terminal domain of NPC1. May bind and mobilize cholesterol that is associated with membranes. NPC2 binds cholesterol with a 1:1 stoichiometry. Can bind a variety of sterols, including lathosterol, desmosterol and the pl [...] | Adhesion G protein-coupled receptor E5b, duplicate 3; Belongs to the G-protein coupled receptor 2 family. | 0.645 |
| npc2 | apoba | ENSDARP00000050398 | ENSDARP00000062792 | NPC intracellular cholesterol transporter 2; Intracellular cholesterol transporter which acts in concert with NPC1 and plays an important role in the egress of cholesterol from the lysosomal compartment. Unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes is transferred by NPC2 to the cholesterol-binding pocket in the N-terminal domain of NPC1. May bind and mobilize cholesterol that is associated with membranes. NPC2 binds cholesterol with a 1:1 stoichiometry. Can bind a variety of sterols, including lathosterol, desmosterol and the pl [...] | Apolipoprotein Ba. | 0.654 |
| npc2 | npc1 | ENSDARP00000050398 | ENSDARP00000144951 | NPC intracellular cholesterol transporter 2; Intracellular cholesterol transporter which acts in concert with NPC1 and plays an important role in the egress of cholesterol from the lysosomal compartment. Unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes is transferred by NPC2 to the cholesterol-binding pocket in the N-terminal domain of NPC1. May bind and mobilize cholesterol that is associated with membranes. NPC2 binds cholesterol with a 1:1 stoichiometry. Can bind a variety of sterols, including lathosterol, desmosterol and the pl [...] | Niemann-Pick disease, type C1. | 0.999 |
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