Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mpped2Metallophosphoesterase domain-containing 2b. (294 aa)    
Predicted Functional Partners:
arl14ep
ADP-ribosylation factor-like 14 effector protein.
      
 0.759
dnajc24
DnaJ (Hsp40) homolog, subfamily C, member 24.
      
 0.741
trmt9b
tRNA methyltransferase 9B.
      
 0.739
uprt
Uracil phosphoribosyltransferase homolog.
    
   0.722
rcn1
Reticulocalbin 1, EF-hand calcium-binding domain.
      
 0.720
immp1l
Mitochondrial inner membrane protease subunit.
      
 0.684
elp4
Elongator complex protein 4; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs; Belongs to the ELP4 family.
      
 0.678
mms19
MMS19 nucleotide excision repair protein homolog; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins (By similarity).
    
   0.632
txndc9
Thioredoxin domain-containing 9.
    
   0.628
rcn3
Reticulocalbin 3, EF-hand calcium-binding domain.
      
 0.597
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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