STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPDEFSAM pointed domain containing ETS transcription factor. (325 aa)    
Predicted Functional Partners:
ilrun
Protein ILRUN; May have a roles as negative regulator of innate antiviral response.
 
    
 0.748
agr2
Anterior gradient protein 2 homolog; Belongs to the AGR family.
   
  
 0.729
ENSDARP00000135683
Uncharacterized protein.
      
 0.692
foxa3
Forkhead box A3.
   
  
 0.689
GALNT3
Polypeptide N-acetylgalactosaminyltransferase.
   
  
 0.609
tipin
TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Important for cell survival after DNA damage or replication stress. May be required fin the replication checkpoint induced by hydroxyurea or ultraviolet light (By similarity).
      
 0.607
gcnt3
Glucosaminyl (N-acetyl) transferase 3, mucin type.
      
 0.584
spink4
Serine peptidase inhibitor, Kazal type 4.
      
 0.563
C10H5orf30
Macrophage immunometabolism regulator; May play a role in immune regulation through regulation of the macrophage function (By similarity). Involved in the recruitment of macrophages in response to injury. May also play a role in trafficking of proteins via its interaction with unc119 family cargo adapters (By similarity). May play a role in ciliary membrane localization.
    
   0.557
atoh1a
Atonal bHLH transcription factor 1a.
      
 0.551
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.