Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPDEFSAM pointed domain containing ETS transcription factor. (325 aa)    
Predicted Functional Partners:
C10H5orf30
Macrophage immunometabolism regulator; May play a role in immune regulation through regulation of the macrophage function (By similarity). Involved in the recruitment of macrophages in response to injury. May also play a role in trafficking of proteins via its interaction with unc119 family cargo adapters (By similarity). May play a role in ciliary membrane localization.
    
   0.926
agr2
Anterior gradient protein 2 homolog; Belongs to the AGR family.
   
 
 0.790
foxa3
Forkhead box A3.
   
  
 0.784
ilrun
Protein ILRUN; May have a roles as negative regulator of innate antiviral response.
 
    
 0.766
unc119a
Unc-119 homolog a (C. elegans).
    
   0.728
unc119b
Protein unc-119 homolog B.
    
   0.728
GALNT3
Polypeptide N-acetylgalactosaminyltransferase.
      
 0.690
ENSDARP00000135683
Uncharacterized protein.
      
 0.667
gcnt3
Glucosaminyl (N-acetyl) transferase 3, mucin type.
   
  
 0.663
muc5.1
Mucin 5.1, oligomeric mucus/gel-forming.
      
 0.661
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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