Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
crim1Cysteine-rich motor neuron 1 protein; May play a role in CNS development by interacting with growth factors implicated in motor neuron differentiation and survival. (1027 aa)    
Predicted Functional Partners:
lxn
Latexin.
      
 0.701
si:dkey-43k4.5
Si:dkey-43k4.5; Belongs to the potassium channel family.
   
 
 0.651
frem1a
Fras1-related extracellular matrix 1a.
    
 0.645
adamts13
ADAM metallopeptidase with thrombospondin type 1 motif, 13.
    
  0.637
gp9
Glycoprotein IX (platelet).
   
 0.631
oma1
Metalloendopeptidase OMA1, mitochondrial; Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of opa1 at S1 position, leading to opa1 inactivation and negative regulation of mitochondrial fusion.
      
 0.622
E7FBD4_DANRE
Si:dkey-288i20.2.
      
 0.605
Q5RJ41_DANRE
Si:ch211-57i17.1.
      
 0.605
s100a10a
Protein S100; Belongs to the S-100 family.
      
 0.598
gp1bb
Glycoprotein Ib platelet subunit beta.
    
 0.598
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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