Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
xpr1bXenotropic and polytropic retrovirus receptor 1 homolog; Plays a role in phosphate homeostasis. Mediates phosphate export from the cell. Binds inositol hexakisphosphate (Ins6P) and similar inositol polyphosphates, such as 5-diphospho- inositol pentakisphosphate (5-InsP7); these are important intracellular signaling molecules (By similarity). (693 aa)    
Predicted Functional Partners:
myorg
Myogenesis-regulating glycosidase (putative); Belongs to the glycosyl hydrolase 31 family.
    
 
 0.889
gpcpd1
Glycerophosphocholine phosphodiesterase 1.
   
 
 0.884
slc20a2
Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
      
 0.839
kidins220a
Kinase D-interacting substrate 220a.
   
 0.765
kidins220b
Kinase D-interacting substrate of 220 kDa B; Downstream target for both neurotrophin and ephrin receptors. May play a role in nerve growth factor (NGF)-induced recruitment of rapgef2 to late endosomes and neurite outgrowth.
   
 0.765
nkpd1
NTPase, KAP family P-loop domain-containing 1.
   
 0.765
nlrc3l
NLR family, CARD domain-containing 3-like.
      
 0.720
gde1
Glycerophosphodiester phosphodiesterase 1.
     
 0.711
fbxo31
F-box protein 31.
      
 0.662
ppip5k1b
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...]
      
 0.662
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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