Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cd36CD36 molecule (thrombospondin receptor); Belongs to the CD36 family. (465 aa)    
Predicted Functional Partners:
thbs1b
Thrombospondin 1b.
    
 0.985
thbs2a
Thrombospondin 2a.
    
 0.975
thbs4b
Thrombospondin-4-B; Adhesive glycoprotein that mediates cell-to-cell and cell-to- matrix interactions and may be involved in various processes including cellular proliferation, migration, adhesion and attachment. May play a role in ER stress response (By similarity); Belongs to the thrombospondin family.
    
 0.965
thbs3a
Thrombospondin-3a; Adhesive glycoprotein that mediates cell-to-cell and cell-to- matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen (By similarity).
    
 0.963
comp
Cartilage oligomeric matrix protein.
    
 0.951
thbs4a
Thrombospondin 4a.
    
  0.950
thbs2b
Thrombospondin 2b.
    
 0.941
thbs3b
Thrombospondin-3b; Adhesive glycoprotein that mediates cell-to-cell and cell-to- matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen (By similarity); Belongs to the thrombospondin family.
    
  0.934
thbs1a
Thrombospondin 1a.
    
 0.892
pparg
Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]
   
 
 0.846
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.