| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSDARP00000136668 | jag1a | ENSDARP00000136668 | ENSDARP00000121170 | Ncstrn_small domain-containing protein. | Protein jagged-1a; Ligand for multiple Notch receptors and involved in the mediation of Notch signaling (By similarity). Seems to be involved in cell-fate decisions. | 0.443 |
| ENSDARP00000136668 | jag1b | ENSDARP00000136668 | ENSDARP00000008197 | Ncstrn_small domain-containing protein. | Protein jagged-1b; Ligand for Notch receptors and involved in the mediation of Notch signaling (By similarity). Seems to be involved in cell-fate decisions. | 0.443 |
| ENSDARP00000136668 | notch1b | ENSDARP00000136668 | ENSDARP00000050854 | Ncstrn_small domain-containing protein. | Notch receptor 1b. | 0.958 |
| ENSDARP00000136668 | psen1 | ENSDARP00000136668 | ENSDARP00000136264 | Ncstrn_small domain-containing protein. | Presenilin-1; Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein). Requires the presence of the other members of the gamma-secretase complex for protease activity. Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins (By similarity); Belongs to the peptidase A22A family. | 0.995 |
| jag1a | ENSDARP00000136668 | ENSDARP00000121170 | ENSDARP00000136668 | Protein jagged-1a; Ligand for multiple Notch receptors and involved in the mediation of Notch signaling (By similarity). Seems to be involved in cell-fate decisions. | Ncstrn_small domain-containing protein. | 0.443 |
| jag1a | jag1b | ENSDARP00000121170 | ENSDARP00000008197 | Protein jagged-1a; Ligand for multiple Notch receptors and involved in the mediation of Notch signaling (By similarity). Seems to be involved in cell-fate decisions. | Protein jagged-1b; Ligand for Notch receptors and involved in the mediation of Notch signaling (By similarity). Seems to be involved in cell-fate decisions. | 0.830 |
| jag1a | lfng | ENSDARP00000121170 | ENSDARP00000031031 | Protein jagged-1a; Ligand for multiple Notch receptors and involved in the mediation of Notch signaling (By similarity). Seems to be involved in cell-fate decisions. | Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Involved in the correct formation of boundaries in the somites and hindbrain (By similarity). Required for Delta-Notch-mediated induction of hypochord cells at the lateral borders of the midline precursor domain. | 0.709 |
| jag1a | maml1 | ENSDARP00000121170 | ENSDARP00000102289 | Protein jagged-1a; Ligand for multiple Notch receptors and involved in the mediation of Notch signaling (By similarity). Seems to be involved in cell-fate decisions. | Mastermind-like transcriptional coactivator 1. | 0.866 |
| jag1a | maml3 | ENSDARP00000121170 | ENSDARP00000115500 | Protein jagged-1a; Ligand for multiple Notch receptors and involved in the mediation of Notch signaling (By similarity). Seems to be involved in cell-fate decisions. | Mastermind-like transcriptional coactivator 3. | 0.851 |
| jag1a | notch1b | ENSDARP00000121170 | ENSDARP00000050854 | Protein jagged-1a; Ligand for multiple Notch receptors and involved in the mediation of Notch signaling (By similarity). Seems to be involved in cell-fate decisions. | Notch receptor 1b. | 0.956 |
| jag1a | psen1 | ENSDARP00000121170 | ENSDARP00000136264 | Protein jagged-1a; Ligand for multiple Notch receptors and involved in the mediation of Notch signaling (By similarity). Seems to be involved in cell-fate decisions. | Presenilin-1; Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein). Requires the presence of the other members of the gamma-secretase complex for protease activity. Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins (By similarity); Belongs to the peptidase A22A family. | 0.536 |
| jag1a | rbpja | ENSDARP00000121170 | ENSDARP00000026585 | Protein jagged-1a; Ligand for multiple Notch receptors and involved in the mediation of Notch signaling (By similarity). Seems to be involved in cell-fate decisions. | Recombination signal-binding protein for immunoglobulin kappa J region a. | 0.922 |
| jag1a | rbpjb | ENSDARP00000121170 | ENSDARP00000087012 | Protein jagged-1a; Ligand for multiple Notch receptors and involved in the mediation of Notch signaling (By similarity). Seems to be involved in cell-fate decisions. | Recombination signal-binding protein for immunoglobulin kappa J region b. | 0.529 |
| jag1a | zmp:0000001236 | ENSDARP00000121170 | ENSDARP00000151452 | Protein jagged-1a; Ligand for multiple Notch receptors and involved in the mediation of Notch signaling (By similarity). Seems to be involved in cell-fate decisions. | MamL-1 domain-containing protein. | 0.849 |
| jag1b | ENSDARP00000136668 | ENSDARP00000008197 | ENSDARP00000136668 | Protein jagged-1b; Ligand for Notch receptors and involved in the mediation of Notch signaling (By similarity). Seems to be involved in cell-fate decisions. | Ncstrn_small domain-containing protein. | 0.443 |
| jag1b | jag1a | ENSDARP00000008197 | ENSDARP00000121170 | Protein jagged-1b; Ligand for Notch receptors and involved in the mediation of Notch signaling (By similarity). Seems to be involved in cell-fate decisions. | Protein jagged-1a; Ligand for multiple Notch receptors and involved in the mediation of Notch signaling (By similarity). Seems to be involved in cell-fate decisions. | 0.830 |
| jag1b | lfng | ENSDARP00000008197 | ENSDARP00000031031 | Protein jagged-1b; Ligand for Notch receptors and involved in the mediation of Notch signaling (By similarity). Seems to be involved in cell-fate decisions. | Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Involved in the correct formation of boundaries in the somites and hindbrain (By similarity). Required for Delta-Notch-mediated induction of hypochord cells at the lateral borders of the midline precursor domain. | 0.486 |
| jag1b | maml1 | ENSDARP00000008197 | ENSDARP00000102289 | Protein jagged-1b; Ligand for Notch receptors and involved in the mediation of Notch signaling (By similarity). Seems to be involved in cell-fate decisions. | Mastermind-like transcriptional coactivator 1. | 0.824 |
| jag1b | maml3 | ENSDARP00000008197 | ENSDARP00000115500 | Protein jagged-1b; Ligand for Notch receptors and involved in the mediation of Notch signaling (By similarity). Seems to be involved in cell-fate decisions. | Mastermind-like transcriptional coactivator 3. | 0.820 |
| jag1b | notch1b | ENSDARP00000008197 | ENSDARP00000050854 | Protein jagged-1b; Ligand for Notch receptors and involved in the mediation of Notch signaling (By similarity). Seems to be involved in cell-fate decisions. | Notch receptor 1b. | 0.953 |