Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
surf4lSurfeit gene 4, like. (269 aa)    
Predicted Functional Partners:
tmed2
Transmembrane p24-trafficking protein 2.
   
 
 0.817
tmed10
Transmembrane emp24-like trafficking protein 10 (Yeast).
   
 
 0.812
gosr1
Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.
    
 
 0.761
lman1
Lectin, mannose-binding, 1.
   
 
 0.739
rer1
Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
   
 
 0.690
tmed9
Transmembrane p24-trafficking protein 9.
   
 
 0.675
tmed4
Transmembrane p24-trafficking protein 4.
   
 
 0.675
ergic1
Endoplasmic reticulum-Golgi intermediate compartment protein 1; Possible role in transport between endoplasmic reticulum and Golgi; Belongs to the ERGIC family.
    
 
 0.672
ergic2
Endoplasmic reticulum-Golgi intermediate compartment protein 2; Possible role in transport between endoplasmic reticulum and Golgi; Belongs to the ERGIC family.
    
 
 0.667
U3JB19_DANRE
Si:ch211-225b10.3.
    
 
 0.667
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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