Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
slc25a46Solute carrier family 25 member 46; May play a role in mitochondrial dynamics by controlling mitochondrial membrane fission. (405 aa)    
Predicted Functional Partners:
slc7a6os
Probable RNA polymerase II nuclear localization protein SLC7A6OS; Directs RNA polymerase II nuclear import.
      
 0.710
opa3
Optic atrophy 3 protein homolog; May play some role in mitochondrial processes; Belongs to the OPA3 family.
   
  
 0.690
mtch2
Mitochondrial carrier homolog 2; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
 
 0.686
march5
E3 ubiquitin-protein ligase MARCH5.
   
 
 0.659
march5l
E3 ubiquitin-protein ligase MARCHF5; Mitochondrial E3 ubiquitin-protein ligase that plays a crucial role in the control of mitochondrial morphology by acting as a positive regulator of mitochondrial fission. May play a role in the prevention of cell senescence acting as a regulator of mitochondrial quality control.
   
 
 0.657
mfn2
Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
   
 
 0.624
slc25a48
Solute carrier family 25 member 48.
      
 0.605
slc25a16
Solute carrier family 25 member 16; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.601
slc35f2
Solute carrier family 35 member F2.
      
 0.573
slc26a11
Solute carrier family 26 member 11.
   
  
 0.558
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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