Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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dmrt3aDoublesex- and mab-3-related transcription factor 3a; Probable transcription factor that plays a role in configuring the spinal circuits controlling motion in vertebrates. Involved in neuronal specification within specific subdivision of spinal cord neurons and in the development of a coordinated locomotor network controlling movements. May regulate transcription (By similarity); Belongs to the DMRT family. (448 aa)    
Predicted Functional Partners:
foxl2a
Forkhead box L2-1.
    
 
 0.735
dmrt2a
Doublesex and mab-3-related transcription factor 2a.
   
  
0.713
slc6a5
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
      
 0.662
tdrd1
Tudor domain-containing protein 1; Plays a central role during spermatogenesis by participating in the repression transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Required for the localization of Piwi proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of corr [...]
      
 0.617
evx2
Even-skipped homeobox 2.
   
 
 0.613
ptar1
Protein prenyltransferase alpha subunit repeat-containing protein 1; Belongs to the protein prenyltransferase subunit alpha family.
      
 0.612
amh
Anti-Mullerian hormone.
      
 0.610
syt14b
Synaptotagmin XIVb.
      
 0.595
wt1a
WT1 transcription factor a.
   
 
 0.594
cfap157
Cilia- and flagella-associated protein 157; Specifically required during spermatogenesis for flagellum morphogenesis and sperm motility; Belongs to the CFAP157 family.
      
 0.590
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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