STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arhgap4bRho GTPase-activating protein 4b. (966 aa)    
Predicted Functional Partners:
rac1a
Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1).
    
 0.612
itsn2a
Intersectin 2a.
   
 
0.607
itsn2b
Intersectin 2b.
   
 
0.605
itsn1
Intersectin 1 (SH3 domain protein).
   
 
0.538
tsen2
TSEN2 tRNA-splicing endonuclease subunit.
    
   0.506
cdc42l2
Cell division cycle 42-like 2.
    
  0.469
rhoac
Rho-related GTP-binding protein RhoA-C; Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers.
    
  0.469
nckipsd
NCK-interacting protein with SH3 domain.
    
 
 0.457
arhgap32a
Rho GTPase-activating protein 32a.
   
 
0.411
waslb
WASP-like actin nucleation-promoting factor b.
   
 
 0.407
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.