Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
fcho2F-BAR domain only protein 2; May function in an early step of clathrin-mediated endocytosis. (848 aa)    
Predicted Functional Partners:
itsn2b
Intersectin 2b.
   
 
 0.900
itsn2a
Intersectin 2a.
   
 
 0.898
agfg1a
ArfGAP with FG repeats 1a.
    
 
 0.882
itsn1
Intersectin 1 (SH3 domain protein).
   
 
 0.869
eps15
Epidermal growth factor receptor pathway substrate 15.
   
 
 0.821
eps15l1b
Epidermal growth factor receptor pathway substrate 15 like 1.
   
 
 0.764
dab2
DAB adaptor protein 2.
    
 
 0.744
maco1a
Macoilin-1; May play a role in the regulation of neuronal activity. Belongs to the macoilin family.
   
  
 0.734
ap1b1
AP complex subunit beta.
   
 
 0.732
bmp2k
BMP2-inducible kinase.
   
  
 0.676
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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