Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
plp1bProteolipid protein 1b. (279 aa)    
Predicted Functional Partners:
mbpb
Myelin basic protein b.
   
 
 0.983
cldnk
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
   
  
 0.844
mbpa
Myelin basic protein a.
   
  
 0.828
mpz
Myelin protein zero.
   
  
 0.813
cnp
2',3'-cyclic nucleotide 3' phosphodiesterase.
   
  
 0.788
tnr
Tenascin R (Restrictin, janusin).
   
    0.783
olig2
Oligodendrocyte lineage transcription factor 2.
   
  
 0.753
slc1a2b
Amino acid transporter.
   
 
 0.749
E7EY09_DANRE
Si:ch211-232b12.5.
      
 0.719
B0R0K9_DANRE
Si:ch211-103n10.5.
      
 0.717
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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