Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
capgaCapping protein (actin filament), gelsolin-like a. (350 aa)    
Predicted Functional Partners:
nfil3-4
Nuclear factor, interleukin 3-regulated, member 4.
      
 0.779
igl1c3
Immunoglobulin light 1 constant 3.
   
  
 0.740
F1QKH0_DANRE
Si:ch211-1a19.2.
      
 0.736
swap70b
Switching B cell complex subunit SWAP70b.
      
 0.720
sid1
Secreted immunoglobulin domain 1.
      
 0.720
pikfyve
Phosphatidylinositol phosphate 5-kinase type III isoform d.
     
  0.695
mrap2a
Melanocortin-2 receptor accessory protein 2A; Inhibitor of melanocortin receptor 4 (mc4r), a receptor involved in energy homeostasis. Plays a role during larval development in the control of energy homeostasis and body weight regulation by decreasing ligand-sensitivity of mc4r and mc4r-mediated generation of cAMP, leading to stimulate growth during larval development. Acts by stabilizing an inactive conformation of mc4r during embryonic development, when all the energy consumed is obtained from the yolk sac, possibly to speed the rapid maturation to the mobile free-feeding juvenile sta [...]
      
 0.683
igic1s1
Immunoglobulin light 3 variable 5.
      
 0.681
pcdh7b
Protocadherin 7b.
      
 0.663
cog6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
   
 
 0.632
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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