STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cyp1d1Cytochrome P450, family 1, subfamily D, polypeptide 1; Belongs to the cytochrome P450 family. (512 aa)    
Predicted Functional Partners:
dtwd1
DTW domain-containing protein 1.
      
 0.839
arnt2
Aryl hydrocarbon receptor nuclear translocator 2; Transcription factor that plays a role in the development of the hypothalamo-pituitary axis. Specifically recognizes the xenobiotic response element (XRE) (By similarity). Isoform 1 acts as a transcriptional activator. Isoform 3 acts as a transcriptional repressor.
    
 
 0.809
ahr1a
Aryl hydrocarbon receptor 1a.
   
 
 0.755
ahr2
Aryl hydrocarbon receptor 2.
   
 
 0.755
cyp8b2
Cytochrome P450, family 8, subfamily B, polypeptide 2.
   
  
 0.630
cyp8b3
Cytochrome P450, family 8, subfamily B, polypeptide 3.
   
  
 0.609
cyp3a65
Cytochrome P450, family 3, subfamily A, polypeptide 65; Belongs to the cytochrome P450 family.
  
0.608
aasdh
Beta-alanine-activating enzyme; Covalently binds beta-alanine in an ATP-dependent manner to form a thioester bond with its phosphopantetheine group and transfers it to an, as yet, unknown acceptor. May be required for a post- translational protein modification or for post-transcriptional modification of an RNA.
  
 0.561
cyp26c1
Cytochrome P450, family 26, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family.
  
   
 0.549
cyb5a
Cytochrome b5 type A (microsomal); Belongs to the cytochrome b5 family.
   
 
 0.548
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: medium (72%) [HD]