Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hs3st1l2Sulfotransferase; Belongs to the sulfotransferase 1 family. (303 aa)    
Predicted Functional Partners:
serpinc1
Serine (Or cysteine) proteinase inhibitor, clade C (Antithrombin), member 1; Belongs to the serpin family.
      
 0.740
glceb
D-glucuronyl C5-epimerase B; Converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acid residues, both in maturing heparan sulfate (HS) and heparin chains. Plays a role in dorso-ventral axis specification during early development, together with glcea, where it may potentiate signaling via the BMP pathway.
      
 0.725
extl3
Exostosin-like glycosyltransferase 3; Belongs to the glycosyltransferase 47 family.
      
 0.710
glcea
Glucuronic acid epimerase a.
      
 0.701
hs6st1b
Heparan-sulfate 6-O-sulfotransferase 1-B; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
      
 0.698
ext2
Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family.
      
 0.656
hs2st1b
Heparan sulfate 2-O-sulfotransferase 1b.
      
 0.601
hs2st1a
Heparan sulfate 2-O-sulfotransferase 1a.
      
 0.601
hs6st3b
Heparan-sulfate 6-O-sulfotransferase 3-B; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
      
 0.595
hs6st1a
Heparan-sulfate 6-O-sulfotransferase 1-A; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
      
 0.537
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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