ISCU protein (Danio rerio) - STRING interaction network

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ISCU

Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (165 aa)

Predicted Functional Partners:

nfs1

0.999

lyrm4

0.991

fxn

0.983

isca2

0.965

nfu1

0.965

fdx2

0.963

scly

0.960

lyrm4-2

0.959

hspa9

0.949

isca1

0.949

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ISCU	fdx2	ENSDARP00000051606	ENSDARP00000131094	Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	Ferredoxin-2, mitochondrial; Essential for heme A and Fe/S protein biosynthesis.	0.963
ISCU	fxn	ENSDARP00000051606	ENSDARP00000115873	Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	Frataxin.	0.983
ISCU	hspa9	ENSDARP00000051606	ENSDARP00000003744	Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	Heat shock protein 9; Belongs to the heat shock protein 70 family.	0.949
ISCU	isca1	ENSDARP00000051606	ENSDARP00000068166	Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	Iron-sulfur cluster assembly 1 homolog, mitochondrial; Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. Probably involved in the binding of an intermediate of Fe/S cluster assembly. Belongs to the HesB/IscA family.	0.949
ISCU	isca2	ENSDARP00000051606	ENSDARP00000055610	Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	Iron-sulfur cluster assembly 2.	0.965
ISCU	lyrm4	ENSDARP00000051606	ENSDARP00000103510	Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	LYR motif-containing protein 4; Required for nuclear and mitochondrial iron-sulfur protein biosynthesis.	0.991
ISCU	lyrm4-2	ENSDARP00000051606	ENSDARP00000147532	Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	Si:ch211-152c8.4; Belongs to the complex I LYR family.	0.959
ISCU	nfs1	ENSDARP00000051606	ENSDARP00000084180	Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	NFS1 nitrogen fixation 1 (S. cerevisiae).	0.999
ISCU	nfu1	ENSDARP00000051606	ENSDARP00000114381	Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae).	0.965
ISCU	scly	ENSDARP00000051606	ENSDARP00000099679	Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	Selenocysteine lyase.	0.960
fdx2	ISCU	ENSDARP00000131094	ENSDARP00000051606	Ferredoxin-2, mitochondrial; Essential for heme A and Fe/S protein biosynthesis.	Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.963
fdx2	fxn	ENSDARP00000131094	ENSDARP00000115873	Ferredoxin-2, mitochondrial; Essential for heme A and Fe/S protein biosynthesis.	Frataxin.	0.796
fdx2	hspa9	ENSDARP00000131094	ENSDARP00000003744	Ferredoxin-2, mitochondrial; Essential for heme A and Fe/S protein biosynthesis.	Heat shock protein 9; Belongs to the heat shock protein 70 family.	0.633
fdx2	isca1	ENSDARP00000131094	ENSDARP00000068166	Ferredoxin-2, mitochondrial; Essential for heme A and Fe/S protein biosynthesis.	Iron-sulfur cluster assembly 1 homolog, mitochondrial; Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. Probably involved in the binding of an intermediate of Fe/S cluster assembly. Belongs to the HesB/IscA family.	0.854
fdx2	isca2	ENSDARP00000131094	ENSDARP00000055610	Ferredoxin-2, mitochondrial; Essential for heme A and Fe/S protein biosynthesis.	Iron-sulfur cluster assembly 2.	0.892
fdx2	lyrm4	ENSDARP00000131094	ENSDARP00000103510	Ferredoxin-2, mitochondrial; Essential for heme A and Fe/S protein biosynthesis.	LYR motif-containing protein 4; Required for nuclear and mitochondrial iron-sulfur protein biosynthesis.	0.921
fdx2	lyrm4-2	ENSDARP00000131094	ENSDARP00000147532	Ferredoxin-2, mitochondrial; Essential for heme A and Fe/S protein biosynthesis.	Si:ch211-152c8.4; Belongs to the complex I LYR family.	0.883
fdx2	nfs1	ENSDARP00000131094	ENSDARP00000084180	Ferredoxin-2, mitochondrial; Essential for heme A and Fe/S protein biosynthesis.	NFS1 nitrogen fixation 1 (S. cerevisiae).	0.978
fdx2	nfu1	ENSDARP00000131094	ENSDARP00000114381	Ferredoxin-2, mitochondrial; Essential for heme A and Fe/S protein biosynthesis.	NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae).	0.879
fdx2	scly	ENSDARP00000131094	ENSDARP00000099679	Ferredoxin-2, mitochondrial; Essential for heme A and Fe/S protein biosynthesis.	Selenocysteine lyase.	0.703

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